In addition, the material in the medium is also accompanied by the deposition of the phenomenon of diffusion. Diffusion is unconditional. The diffusion is inversely proportional to the mass of the material, and the smaller the particle is, the more serious the diffusion is. While the settlement is relative and conditional, it is to be subjected to external forces. The settlement is proportional to the weight of the body, the bigger the particle is, the faster the settlement is. Particles of less than a few microns, such as viruses or proteins, they are in a solution to a colloidal or semi colloidal state, the use of gravity is not likely to observe the settlement process.